Progress of relationship between Helicobacter pylori infection and colorectal cancer / 肿瘤研究与临床

Studies on the relationship between Helicobacter pylori infection and colorectal cancer have been controversial in recent years. The Chinese "eat-together system" dietary culture and the life style of family gathering result in a high infection rate of Helicobacter pylori, and the relationship between Helicobacter pylori and tumors has thereupon become one of the research hotspots. Studies have shown that Helicobacter pylori infection may promote the occurrence of colorectal precancerous lesions and colorectal cancer by inducing hypergastrinemia, destroying intestinal microecology, suppressing immune function and other ways. This article reviews the research progress on the relationship between Helicobacter pylori infection and colorectal cancer and its mechanism.

Application of laparoscopic ventral rectal fixation in rectal prolapse / 中华普通外科杂志

Objective To explore the clinical value of laparoscopic ventral rectopexy for rectal prolapse.Methods From Jan 2013 to Jan 2017,26 patients with complete rectal prolapse were divided into control group (15 patients) undergoing laparoscopic rectal fixation,and 11 patients in study group were treated with rectal ventral fixation.Results There was no significant difference in operation time,bleeding volume and exhaust time between the two groups (t =1.839,0.138,0.932,all P ＞ 0.05).In the study group,2 cases had temporarily postoperative fever.Following up for 12 to 36 months,1 case recurred in the control group and 1 case in the study group.The length of rectal prolapse was about 2 cm.Of the 7 patients with constipation in the control group,symptoms disappeared in 2 cases,symptoms improved in another 2 cases,and 5 cases had new constipation.Of the 4 patients with anal incontinence,2 cases had recovered and 1 case had symptoms improved.Among the 6 patients with constipation in the study group,symptoms disappeared in 3 cases,symptoms improved in 2 cases.Of the 3 patients with pelvic prolapse,2 cases recovered and 1 case improved.The pelvic prolapse and constipation in the study group was less severe than that in the control group (x2 =4.909,P ＜ 0.05).Conclusion Laparoscopic rectal ventral fixation for the treatment of complete rectal prolapse is less traumatic,safor and more effective.